▪ 약물의 분류: 교감신경흥분제(혈압을 높이고 기관지를 확장시킴)

▪ 임신부 약물등급(US FDA): 정보없음

▪ 임신부 안전 및 기형발생정보 :
A controlled study in humans did not associate ephedrine exposure during pregnancy with an increase in malformation risk. Ephedrine has been used for weight loss, and weight loss during pregnancy might have independent adverse effects.

▪ 모유수유부 약물등급(Medication and Mother’s MilK): L4

▪ 모유수유 안전 및 유해성정보 :
Ephedrine was found in human milk before and after the twice-daily ingestion of 2.5 g powdered kudzu root extract. The pre-treatment ephedrine concentration in milk was 9.3 mcg/mL before and 47.2 mcg/mL after treatment. It is not known whether ephedrine therapy affects nursing. There is a case report of a baby with disturbed behavior who was exposed through breastfeeding to ephedrine and to an antihistamine. The child`s symptoms resolved when nursing was discontinued.

▪ 한국마더세이프전문상담센터 DB 정보 (모태독성학2016):

1) 기형발생정보
에페드린에 노출된 후 추적된 임신부는 총 91례이었으며 초기 노출 후 자연유산율은 5.4%(5/91)이었다. 임신 37주 이전의 조산률은 7.3%(6/82), 2,500 g 미만의 저체중증은 3.7%(3/81)
이었다. 주요기형발생은 3.7%(3/82): bilateral inguinal hernia(1), micro penis with small right testis(1), choledochal cyst(1)가 있었다. 그리고 신생아 사망 1례가 있었다.

2) 모유 수유 시 독성 및 적합성 정보
수유부-수유아 1쌍 중 부작용 사례는 없었다.

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